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Fig. 8 | Journal of Experimental & Clinical Cancer Research

Fig. 8

From: Exosome-mediated transfer of lncRNA PART1 induces gefitinib resistance in esophageal squamous cell carcinoma via functioning as a competing endogenous RNA

Fig. 8

LncRNA PART1 promotes gefitinib resistance in vivo. a Photographs of tumors that developed in xenograft transplanted nude mouse tumor models treated orally with once daily 150 mg/kg gefitinib or 1% Tween80 as control for four weeks in different groups. The group settings are as follows: Group I (Lv-PART1-transfected cells + gefitinib treatment), Group II (Lv-PART1-transfected cells + 1% Tween80), Group II (Lv-NC-transfected cells + gefitinib treatment), Group III (Lv-NC-transfected cells + 1% Tween80). b Weights of tumors that developed in xenografts from different groups. *P < 0.05, ***P < 0.001 compared to respective groups. c IHC analysis of expression levels of respective apoptosis markers in group I and group III. *P < 0.05, **P < 0.01 compared to Group III

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