Long noncoding RNA HEGBC promotes tumorigenesis and metastasis of gallbladder cancer via forming a positive feedback loop with IL-11/STAT3 signaling pathway

Table 1 Correlation between HEGBC expression and clinicopathologic characteristics of gallbladder cancer patients

Variables	lncRNA-HEGBC		Chi-square	P-value^b
Variables	Low	High^a
All cases	51	51
Age			0.634	0.426
≥ 60	30	26
< 60	21	25
Gender			0.367	0.545
Male	19	22
Female	32	29
Serum total bilirubin			0.706	0.401
≥ 17.1 μM	15	19
< 17.1 μM	36	32
CA19–9			2.519	0.113
Positive (≥37 U/ml)	23	31
Negative (< 37 U/ml)	28	20
Tumor differentiation			0.158	0.691
Well-moderately	29	27
Poorly	22	24
T status			62.769	0.000
T1 + T2	45	5
T3 + T4	6	46
N status			48.337	0.000
N0	45	10
N1 + N2	6	41
TNM stage			54.440	0.000
I-II	41	4
III-IV	10	47

^aThe median expression level of HEGBC was used as the cutoff
^bPearson chi-square tests were used to analyze the correlation between the expression levels of HEGBC and clinical features

ISSN: 1756-9966