Fig. 2

RIF1 promotes EOC cell growth in vitro. a-d Efficiency of RIF1 knockdown (RIF1 KD) by two shRNAs and RIF1 overexpression (RIF1 over) in OVCAR3 and A2780 cells was verified by real-time qPCR (a and b) and western blot (c and d). e and f Influence of RIF1 knockdown and overexpression on the cell viability of OVCAR3 (e) and A2780 (f) cells measured by the MTS assay. g and h Effect of RIF1 knockdown and overexpression on colony formation was measured in OVCAR3 and A2780 cells. Data were presented as mean ± SD of three independent experiments. * P < 0.05, ** P < 0.01, *** P < 0.001