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Table 2 Multivariate Cox proportional hazard regression analysis for overall survival in patients with osteosarcoma

From: TSSC3 promotes autophagy via inactivating the Src-mediated PI3K/Akt/mTOR pathway to suppress tumorigenesis and metastasis in osteosarcoma, and predicts a favorable prognosis

Variable

No.

Hazard ratio (95% Confidence interval)

P

Tumor size, cm, ≥ 8 cm (vs. <  8 cm)

17/58

3.657 (1.592 to 8.404)

0.002*

Lung metastasis (yes vs. no)

20/58

7.053 (2.975 to 16.723)

< 0.001*

TSSC3 negative expression (vs. positive expression)

41/58

3.795 (1.126 to 12.785)

0.031*

  1. *With significant difference (P < 0.05)