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Table 2 Multivariate Cox proportional hazard regression analysis for overall survival in patients with osteosarcoma

From: TSSC3 promotes autophagy via inactivating the Src-mediated PI3K/Akt/mTOR pathway to suppress tumorigenesis and metastasis in osteosarcoma, and predicts a favorable prognosis

Variable No. Hazard ratio (95% Confidence interval) P
Tumor size, cm, ≥ 8 cm (vs. <  8 cm) 17/58 3.657 (1.592 to 8.404) 0.002*
Lung metastasis (yes vs. no) 20/58 7.053 (2.975 to 16.723) < 0.001*
TSSC3 negative expression (vs. positive expression) 41/58 3.795 (1.126 to 12.785) 0.031*
  1. *With significant difference (P < 0.05)