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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Triptolide inhibits Epstein-Barr nuclear antigen 1 expression by increasing sensitivity of mitochondria apoptosis of nasopharyngeal carcinoma cells

Fig. 2

TP arrests cell cycles and induces apoptosis in EBV-positive NPC cells. a HONE1/Akata and (b) HK1/Akata cells were treated with DMSO control (0.01%) or TP (50 nM) for 24 h. The distribution of cell cycle was determined by flow cytometry. c The cell cycle distribution is quantified by the bar graphs. d HONE1/Akata and HK1/Akata cells were treated with DMSO control (0.01%) or TP (100 nM) for 24 hand 48 h, respectively. Apoptosis assay was performed by flow cytometry. e Four kinds of NPC cells were treated with DMSO control (0.01%) or TP for 48 h, protein expression was determined by Western blotting assay. (*: P < 0.05; **: P < 0.01; ***: P < 0.001)

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