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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: IL-6-mediated cross-talk between human preadipocytes and ductal carcinoma in situ in breast cancer progression

Fig. 5

Xenograft tumor volumes in mice were decreased by peritoneal injections of IL-6 neutralizing antibody. a In vivo experimental design and treatment schedule with the IL-6 neutralizing antibody (IL-6 NAb, 2 mg/kg). b Ultrasound images of xenograft tumors from four mice in each experimental group at 10 weeks post-injection and after two treatments of IL-6 NAb. Two orthogonal images in the X- and Y-axis were obtained. c Gross images of the tumors removed from four mice in each group. Bar = 10 mm. d Tumor volumes (means ± standard errors) measured from four mice in each group. e Representative H&E images of whole tumor tissue slides removed from mice in each group

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