Table 1 Cytokine and adipokine levels in conditioned medium of single or co-cultured human preadipocytes and MCF10DCIS.com cells
| Â | MCF10DCIS.com (pg/ml) | Preadipocyte (pg/ml) | Co-culture (pg/ml) |
|---|---|---|---|
Adiponectin | 116.5 ± 27.6 | 22.69 ± 13.6 | 74.2 ± 29.4 |
Leptin | OOR< | OOR< | OOR< |
Adipsin | 2.2 ± 0.0 | 1236.0 ± 128.5 | 1129.0 ± 158.0 |
Resistin | 44.6 ± 6.63 | 42.4 ± 4.9 | 43.8 ± 4.2 |
PAI-1 | 1069.0 ± 55.9 | 17,568.0 ± 1213.0 | 16,371.0 ± 1418.0 |
CCL2 | 1.3 ± 0.1 | 1825.0 ± 149.0 | 2160.0 ± 68.4 |
CRP | 0.22 ± 0.0 | 2.53 ± 0.0 | 2.53 ± 0.0 |
TGF-β1 | OOR< | OOR< | OOR< |
TGF-β2 | OOR< | OOR< | OOR< |
TGF-β3 | OOR< | OOR< | OOR< |
IL-2 | 2.30 ± 0.3 | OOR< | OOR< |
IL-4 | 0.26 ± 0.05 | 0.17 ± 0.0 | 0.17 ± 0.03 |
IL-5 | 0.26 ± 0.05 | 0.15 ± 0.02 | 0.17 ± 0.03 |
IL-6 | 20.8 ± 0.4 | 6066.0 ± 138.7 | 11,683.0 ± 678.3 |
IL-10 | 1.14 ± 0.06 | 0.77 ± 0.04 | 0.78 ± 0.04 |
IL-12(p70) | 0.94 ± 0.03 | 0.81 ± 0.06 | 0.90 ± 0.03 |
IL-13 | 0.24 ± 0.06 | 0.24 ± 0.06 | 0.24 ± 0.0 |
GM-CSF | 0.60 ± 0.27 | OOR< | OOR < − |
INF-γ | OOR< | 0.91 ± 0.18 | OOR< |
TNF-α | 1.93 ± 0.17 | 1.59 ± 0.13 | 1.82 ± 0.13 |
MMP-1 | 29.5 ± 1.6 | 908.6 ± 11.1 | 787.7 ± 18.9 |
MMP-2 | 360.0 ± 11.2 | 32,069.0 ± 6545 | 7284.0 ± 435.4 |
MMP-3 | OOR< | 665.8 ± 14.1 | 640.0 ± 32.5 |
MMP-9 | 775.7 ± 39.6 | 199.6 ± 3.6 | 192.3 ± 14.3 |
MMP-12 | 0.16 ± 0.16 | OOR< | OOR< |
MMP-13 | OOR< | OOR< | OOR< |