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Table 1 Cytokine and adipokine levels in conditioned medium of single or co-cultured human preadipocytes and MCF10DCIS.com cells

From: IL-6-mediated cross-talk between human preadipocytes and ductal carcinoma in situ in breast cancer progression

  MCF10DCIS.com (pg/ml) Preadipocyte (pg/ml) Co-culture (pg/ml)
Adiponectin 116.5 ± 27.6 22.69 ± 13.6 74.2 ± 29.4
Leptin OOR< OOR< OOR<
Adipsin 2.2 ± 0.0 1236.0 ± 128.5 1129.0 ± 158.0
Resistin 44.6 ± 6.63 42.4 ± 4.9 43.8 ± 4.2
PAI-1 1069.0 ± 55.9 17,568.0 ± 1213.0 16,371.0 ± 1418.0
CCL2 1.3 ± 0.1 1825.0 ± 149.0 2160.0 ± 68.4
CRP 0.22 ± 0.0 2.53 ± 0.0 2.53 ± 0.0
TGF-β1 OOR< OOR< OOR<
TGF-β2 OOR< OOR< OOR<
TGF-β3 OOR< OOR< OOR<
IL-2 2.30 ± 0.3 OOR< OOR<
IL-4 0.26 ± 0.05 0.17 ± 0.0 0.17 ± 0.03
IL-5 0.26 ± 0.05 0.15 ± 0.02 0.17 ± 0.03
IL-6 20.8 ± 0.4 6066.0 ± 138.7 11,683.0 ± 678.3
IL-10 1.14 ± 0.06 0.77 ± 0.04 0.78 ± 0.04
IL-12(p70) 0.94 ± 0.03 0.81 ± 0.06 0.90 ± 0.03
IL-13 0.24 ± 0.06 0.24 ± 0.06 0.24 ± 0.0
GM-CSF 0.60 ± 0.27 OOR< OOR < −
INF-γ OOR< 0.91 ± 0.18 OOR<
TNF-α 1.93 ± 0.17 1.59 ± 0.13 1.82 ± 0.13
MMP-1 29.5 ± 1.6 908.6 ± 11.1 787.7 ± 18.9
MMP-2 360.0 ± 11.2 32,069.0 ± 6545 7284.0 ± 435.4
MMP-3 OOR< 665.8 ± 14.1 640.0 ± 32.5
MMP-9 775.7 ± 39.6 199.6 ± 3.6 192.3 ± 14.3
MMP-12 0.16 ± 0.16 OOR< OOR<
MMP-13 OOR< OOR< OOR<
  1. OOR<, out of range below