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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Renal cancer: new models and approach for personalizing therapy

Fig. 2

Reverse Phase Protein Array (RPPA) relative quantification. a Two-way unsupervised hierarchical clustering of 18 samples classified by grading as G2 (n = 7), G3 (n = 8) and G4 (n = 3) for the expression of endpoints belonging to the angiogenesis pathway showed as heatmap. b Two- way unsupervised hierarchical clustering of 18 samples classified by grading as G2 (n = 7), G3 (n = 8) and G4 (n = 3) for the expression of endpoints belonging to the mTOR pathway showed as heatmap. c Two-way hierarchical clustering of 14 samples classified as progressive (Progr. n = 5) and non-progressive (No Progr. n = 9) tumors and with a documented follow-up within 24 months clustered for the expression of 17 significant endpoints after non parametric test. Significant p value ≤0.05. In all the heatmaps the expression levels are represented as red (high) or green (low), with average values in black

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