Fig. 6From: MiR-452 promotes an aggressive colorectal cancer phenotype by regulating a Wnt/β-catenin positive feedback loopFunction of miR-452 to promote CRC can be inbibited by repressing GSK3β. a, b, c, overexpression of GSK3β reversed cell growth induced by miR-452 as determined by MTT(A) and transwell assays (b, c). d, tumor metastasis model. Overexpression of GSK3β decreased metastasis induced by miR-452 (n = 6)Back to article page