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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair

Fig. 2

HMGB1 knockdown enhanced the inhibitory effect of chemotherapy in MM cells. a: MM cells (RPMI8226, CAG, MM.1S) were transfected with HMGB1 knockdown lentivirus, and the transfection effect was observed with a fluorescence microscope; b, c, d: qRT-PCR (b), western blot and densitometric analysis of the western blot results (c) were used to verify HMGB1 knockdown effect (n = 3); d: The CCK8 assay was used to determine the proliferation of MM cells after HMGB1 knockdown (n = 3, p > 0.05); e: The CCK8 assay was used to analyze the inhibitory effect of Dex after HMGB1 knockdown (n = 3, P>0.05) (*P<0.05,**P<0.01,***P<0.001)

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