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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: HMGB1 knockdown increases MM cell vulnerability by regulating autophagy and DNA damage repair

Fig. 4

Changes of MM survival and apoptosis related genes after HMGB1 knockdown. a: Heatmap of the Affymetrix HTA 2.0 array results in RPMI8226 and CAG cells showing that the DEPTOR, Bcl-2, Bcl-xl, and Mcl1 levels were decreased; b, c,: qRT-PCR (B) and western blotting (c) were used to verify the array results; d: Densitometric analysis of the protein levels of DEPTOR, Bcl-2, and Bcl-xl (n = 3, *p < 0.05, **p < 0.01, ***p < 0.001)

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