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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: FOXC1 induces cancer stem cell-like properties through upregulation of beta-catenin in NSCLC

Fig. 2

FOXC1 induces stemness of NSCLC cells in vitro. a FOXC1 protein levels in NSCLC cells were detected by western blotting. b and c FOXC1 mRNA and protein levels were stably downregulated in A549 cells and upregulated in NCI-H1299 cells. d and e The percentage of CD133+ cells was analyzed by flow cytometry. f and g Representative images (left) and numbers (right) of spheres (diameter > 100 μm). h and i Protein and mRNA levels of SOX2, Oct4, NANOG and ABCG2. All experiments were independently repeated three times. The bar graph presents the mean ± SD. *P < 0.05, **P < 0.01

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