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Table 1 Relationship between miR-1-3p and clinicopathologic variables in patients with prostate cancer

From: The putative tumour suppressor miR-1-3p modulates prostate cancer cell aggressiveness by repressing E2F5 and PFTK1

Variables miR-1-3p P value
All cases Low expression High expression
(n = 124) (n = 54) (n = 70)
Age
  ≥ 65y 70 30 (42.9%) 40 (57.1%) 0.860
  < 65y 54 24 (44.4%) 30 (55.6%)
Serum PSA
  ≥ 10 ng/ml 74 35 (47.3%) 39 (52.7%) 0.306
  < 10 ng/ml 50 19 (38.0%) 31 (62.0%)
Gleason score
  ≥ 7 76 42 (55.3%) 34 (44.7%) 0.001
  < 7 48 12 (25.0%) 36 (76.0%)
pT stage
  < T3 35 23 (65.7%) 12 (34.3%) 0.002
  ≥ T3 89 31 (34.8%) 58 (65.2%)
Lymph node metastasis
 Presence 31 20 (64.5%) 11 (35.5%) 0.012
 Absence 93 34 (36.6%) 59 (63.4%)
Seminal vesicle invasion
 Presence 33 19 (57.6%) 14 (42.4%) 0.164
 Absence 81 35 (43.2%) 46 (56.8%)
Biochemical recurrence
 Presence 14 9 (64.3%) 5 (35.7%) 0.097
 Absence 110 45 (40.9%) 65 (59.1%)