Table 3 Tumor-derived exosomes in the targeted therapy of NSCLC
From: The roles of tumor-derived exosomes in non-small cell lung cancer and their clinical implications
Potential value | Methods | References |
|---|---|---|
A tool for drug delivery | Use electroporation or lipofection | |
A direct target for reducing the content | Blood purification: ADAPT, hollow fiber filtration technology Change the local pH of the tumor: PPIs Drug usage: GW4869, amiloride, diannexin Interfere with signal pathway: knockout Rab27, SYTL4 ,EXPH5, ISGylation and syndecan-syntenin-ALIX | |
Other targets | let-7, LKB1, CD9, CD63, surviving, miR-302b |