Fig. 7

ISL and THC block metastatic potential of lung cancer cells. a H&E staining of tumor tissues excised from mice treated with vehicle, ISL or THC. Arrows point at pathological nuclear divisions. Images: 200×; Scale bars: 50 μm. b Metastatic nodules in lungs excised from mice treated with vehicle, ISL or THC. #, p < 0.001 vs vehicle. c Images of H&E staining of lungs excised from mice treated with vehicle, ISL or THC. Arrows point at metastatic nodules. Images: 100×; Scale bars: 200 μm. d Representative pictures of immunohistochemical staining of phosphor-Cortactin (Tyr421) and phosphor-FAK (Tyr925) in tumor tissues. Images: 100×; Scale bars: 200 μm