Fig. 7
Effect of erlotinib, nelfinavir, nitroxoline and their combinations on clonogenic activity of AsPC-1, Capan-2 and BxPC-3. The effects on clonogenic activity of nelfinavir, or nitroxoline at low (a, c and e), or high concentrations (b, d and f) as single agents and in combinations, with or without erlotinib, were evaluated by a colony forming assay. Data shown in the histograms are the means ± SD of two independent experiments. Representative images of clonogenic assay are shown in Additional file 3: Figure S1. *Statistically significant differences as compared to the vehicle (**p < 0.01; ***p < 0.001; ****p < 0.0001)