Fig. 4
From: miR-203 inhibits ovarian tumor metastasis by targeting BIRC5 and attenuating the TGFβ pathway
miR-203 expression inhibits primary tumor growth in ovaries. a, Bioimaging of mice at one month following intrabursal injection of miR-203 expressing and control SKOV3 cells. b Primary tumor in ovaries were imaged at two months following intrabursal injection (n = 5, **p < 0.01). c. Tumor weight in primary ovaries in mice intrabursally injected with miR-203-expressing and control SKOV3 cells (**p < 0.01). d. H&E stained sections of primary tumor in ovaries. e. Western blot analysis of survivin, EMT markers, and phospho- and total SMAD2 from tumors in ovaries (n = 3, **p < 0.01; ***p < 0.001). f, g, h. Immunofluorescent staining of survivin (f) and EMT markers including cytokeratin-7 (g) and vimentin (h)