Fig. 7

Exosomal miR-155 regulates angiogenesis in vivo. a, g The schematic drawing show the positions where the cells were injected. b, h The pictures show the isolated tumors. The tumors in the same positions in each group are from the same mouse. c, d, i, and j The tumor size and weight (means ± SEM) of different treatment groups. * P < 0.05, ** P < 0.01. e, f, k, and l Representative fluorescence microscopy images and the quantitative analysis of MVD of the xenografts. * P < 0.05. ** P < 0.01. Student’s t-tests. Scale bar, 50 μm. Anti-NC: inhibitor negative control. Anti-miR-155: miR-155 inhibitor. DAPI: 4′6-diamidino-2-phenylindole. Exo: exosomes. MiR-NC: miR-negative control. MVD: microvessel density