Table 1 Schematic view of activities and functions of c-Myc cofactors
From: Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis
Cofactors | Complex | Activity | Function |
|---|---|---|---|
Che-1 | - | Activator | Proliferation |
INI1 | Swi/Snf | Repressor | Trascription |
BPTF | Nurf | Activator | Tumor initiation Tumor progression |
YAP | Yap/Taz | Activator | Proliferation |
Tumorigenesis | |||
HSF1 | - | Activator | Tumorigenesis |
De Novo Lipogenesis | |||
Mitochondrial Biogenesis | |||
Polyamine metabolism | |||
Glycolysis |