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Table 1 Schematic view of activities and functions of c-Myc cofactors

From: Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis

Cofactors Complex Activity Function
Che-1 - Activator Proliferation
INI1 Swi/Snf Repressor Trascription
BPTF Nurf Activator Tumor initiation Tumor progression
YAP Yap/Taz Activator Proliferation
HSF1 - Activator Tumorigenesis
De Novo Lipogenesis
Mitochondrial Biogenesis
Polyamine metabolism