Fig. 9

The function of AFAP1-AS1, 423-5p, and FOSL2 in the metastasis of nasopharyngeal carcinoma 5-8F cells in vivo. a. Forty nude mice were randomly divided into 4 groups with 10 mice per group. Three experimental groups were injected with 5-8F cells transfected with the AFAP1-AS1 overexpression plasmid, miR-423-5p mimics, or the FOSL2 overexpression plasmid through the tail veins, and the control group was injected with 5-8F mock cells (NC). After 8 weeks, the nude mice were sacrificed, and the metastatic tumors were observed (upper panel). Representative lung tissue and metastatic nodes are indicated by arrows (lower panel). b. Metastatic nodes per lung in each group