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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas

Fig. 3

SLC9A1 mRNA expression is related with angiogenesis in gene ontology analysis. a Gene ontology (GO) analysis of positively related biological process shows that NHE1-associated genes are enriched in extracellular matrix organization, angiogenesis and cell adhesion in CGGA datasets. b The heatmaps display SLC9A1-related genes in CGGA cohorts. c Gene Set Enrichment Analysis (GSEA) indicated a stronger angiogenesis phenotype in the case with high NHE1 expression in CGGA dataset. q, adjust p value. d NHE1 mRNA expression was highest in the tumor area of microvascular proliferation compared with other areas in the gliomas from the Ivy Glioblastoma Atlas Project. *, P < 0.05; **, P < 0.01; ***, p < 0.001

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