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Table 1 Univariate and Multivariate Analysis of clinical prognostic parameters in CGGA cohort

From: Elevated Na/H exchanger 1 (SLC9A1) emerges as a marker for tumorigenesis and prognosis in gliomas

Variable

Total No.

Univariate analysisa

Multivariate analysisa, b

P value

HR (95% CI)

P value

HR (95% CI)

NHE1 expression

310

<0.001

3.400 (2.427–4.761)

0.033

1.578 (1.038–2.399)

Age at diagnosis

310

<0.001

1.038 (1.023–1.054)

0.995

–

Gender

310

0.345

0.847 (0.600–1.195)

0.461

–

WHO Grade

310

<0.001

3.477 (2.716–4.452)

<0.001

2.888 (2.204–3.784)

IDH mutation

310

<0.001

0.244 (0.170–0.350)

0.017

0.599 (0.393–0.914)

  1. aCox regression analysis
  2. bFurther adjusting age and gender