Table 3 The association between CLDN7 methylation status and clinicopathologic features in 108 ccRCC patients from Peking University First Hospital (*, p < 0.05. **, p < 0.01)
Clinicopathological Features | Number | CLDN7 Methylation Status | p Value | |
|---|---|---|---|---|
Methylated | Unmethylated | |||
Overall | 108 | 34 (31.5%) | 74 (68.5%) | |
Gender | ||||
 Male | 73 | 26 (35.6%) | 47 (64.4%) | 0.181 |
 Female | 35 | 8 (22.9%) | 27 (77.1%) | |
Age (years) | ||||
  < 56 (Median) | 59 | 12 (20.3%) | 47 (79.7%) | 0.006** |
  ≥ 56 | 49 | 22 (44.9%) | 27 (55.1%) | |
Pathologic T | ||||
 T1a | 51 | 13 (25.5%) | 38 (74.5%) | 0.038* |
 T1b | 29 | 10 (34.5%) | 19 (65.5%) | |
 T2 | 7 | 0 | 7 (100%) | |
 T3 | 21 | 11 (52.4%) | 10 (47.6%) | |
Hisologic grade | ||||
 G1 | 38 | 6 (15.8%) | 32 (84.2%) | 0.032* |
 G2 | 59 | 23 (39.0%) | 36 (61.0%) | |
 G3 | 11 | 5 (45.5%) | 6 (54.5%) | |