The deubiquitinating enzyme UCHL1 is a favorable prognostic marker in neuroblastoma as it promotes neuronal differentiation

Table 4 Multivariable analyses in the Oberthuer dataset

Subject dataset	Covariates	OS		EFS
Subject dataset	Covariates	HR (95% CI)	P	HR (95% CI)	P
Oberthuer dataset^a
UCHL1 expression		0.338 (0.116–0.980)	0.046	0.476 (0.228–0.994)	0.048
Age (< > 18 months)		5.420 (2.249–13.062)	< 0.001	2.292 (1.340–3.919)	0.002
MYCN status (+/− amplification)		5.413 (2.706–10.827)	< 0.001	2.417 (1.443–4.048)	0.001
Stage (4, 4S vs 1, 2, 3)		3.858 (1.732–8.595)	0.001	2.218 (1.252–3.930)	0.006

^aFour patients without survival information were not included in the Oberthuer dataset

ISSN: 1756-9966