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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Tunicamycin specifically aggravates ER stress and overcomes chemoresistance in multidrug-resistant gastric cancer cells by inhibiting N-glycosylation

Fig. 1

Tunicamycin exerts strong cytotoxic effects on MDR GC cells, which correlates with basal ER stress. a Cell survival after Tu treatment for 48 h assayed by CCK-8. Tu, tunicamycin. The values in the untreated group are identified as the baseline, namely 100% survival. b Expressions of ER stress-associated proteins in cells without treatment. β-actin served as the loading control. All proteins were normalized to β-actin. ER, endoplasmic reticulum; 7901, SGC7901; ADR, SGC7901/ADR; VCR, SGC7901/VCR; 823, BGC823; 45, MKN45; GES, human immortalized gastric epithelial cell line

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