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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Long noncoding RNA LINC00511 contributes to breast cancer tumourigenesis and stemness by inducing the miR-185-3p/E2F1/Nanog axis

Fig. 3

LncRNA LINC00511 contributes to the maintenance of breast cancer CSC characteristic. a LINC00511 expression in breast cancer cell lines MDA-MB-468, MDA-MB-231, MDA-MB-453, and MCF-7 and normal cell lines (MCF-10A). b, c Breast cancer cell MDA-MB-231, and MCF-7 LINC00511 expression. d Stem factor (Oct4, Nanog, SOX2) expression in MDA-MB-231 cells transfected with shRNA for LINC00511. e The stem factors (Oct4, Nanog, SOX2) expression in MCF-7 cells transfected with enhanced LINC00511 plasmids. f, g Mammosphere diameter and quantity when transfected with shRNA for LINC00511. h, i Mammosphere diameter and quantity when transfected with enhanced LINC00511 plasmids. ** indicates p value less than 0.01. * indicates p value less than 0.05

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