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Fig. 5 | Journal of Experimental & Clinical Cancer Research

Fig. 5

From: GABA, glutamine, glutamate oxidation and succinic semialdehyde dehydrogenase expression in human gliomas

Fig. 5

GABA oxidation and SSADH expression differences in glioma cell lines; and common SSADH expression in human glioblastoma/glioma samples. a Oxygen consumption rates after using GABA - as an energy substrate - in U251 wt, U251 IDH1m, U87 MG and U373 MG cells in D5030 (representative oxygen consumption curves - Seahorse measurements). b SSADH expression in U251 wt, U251 IDH1m, U87 MG and U373 MG cells (representative Western blot results). c Summarised data about the evaluation of SSADH expressions in wt and IDH1m human samples (upper diagram) and in different human glioma types (lower diagram) and representative IHC stainings with HE counterstaining (DAB-brown staining, magnification 200×; normal human brain tissue and kidney were used as controls). ODG-oligodendroglioma, AC-astrocytoma and GBM-primer glioblastoma

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