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Table 1 Univariate and multivariable analyses of factors predictive of poor overall survival in pancreatic cancer patients

From: LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer

Variables Univariate analysis Multivariate analysis
Overall survival 95% confidence interval P value Hazard ratio 95% confidence interval P value
(Median ± SE,months)
Sex    0.726    
 Male 10 ± 1.063 7.917–12.083     
 Female 11 ± 4.433 2.311–19.689     
Age(years old)    0.379    
 <65 11 ± 0.980 9.078–12.922     
  ≥ 65 7 ± 0.833 5.367–8.633     
Locations    0.234    
 Head 10 ± 1.440 7.178–12.822     
 Body-tail 10 ± 1.571 6.921–13.079     
Perineuronal/vascular/lymphatic invasion    0.280    
 No 11 ± 2.60 5.905–16.095     
 Yes 10.0 ± 0.957 8.125–11.875     
Tumor staging    0.594    
 T1/T2 10.0 ± 1.201 7.646–12.354     
 T3/T4 10.0 ± 1.474 7.112–12.888     
Lymph node staging    0.049 2.053 1.228–3.433 0.006
 N0 10 ± 3.499 3.141–16.859     
 N1/N2 10 ± 1.533 6.996–13.004     
Differential degree    0.002 2.737 1.614–4.644 0.000
 High/ moderate 12 ± 2.854 6.406–17.594     
 Low 6 ± 1.076 3.890–8.110     
TNM staging    0.614    
 I 10 ± 3.177 3.772–16.228     
 II/III 10 ± 0.867 8.301–11.699     
LAT2 expression    0.008 1.912 1.122–3.258 0.017
 Low 23 ± 9.142 5.081–40.919     
 High 9 ± 0.802 7.429–10.571