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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Mutated Von Hippel-Lindau-renal cell carcinoma (RCC) promotes patients specific natural killer (NK) cytotoxicity

Fig. 2

Isolated NKs from VHL-MUT-RCC patients show higher cytolytic capacity against autologous tumor cells. a-b Flow cytometry plots represent the percent NK cells isolated from 4 RCC patients (#24, #25, #26 VHL-MUT and #29 VHL-WT patients) that express CD107a following no stimulation (NK no target cells) and stimulation with K562, autologous tumor cells, A498 VHL-MUT and SN12C VHL-WT cell lines. Isolated NK cells were activated overnight with IL-2 (100 U/mL). Assays were performed at the indicated effector-target ratio (10E:1 T; 5E:1 T)

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