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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Mutated Von Hippel-Lindau-renal cell carcinoma (RCC) promotes patients specific natural killer (NK) cytotoxicity

Fig. 3

Higher NKp46+ cells infiltration and expression of NKp30 and NKp46 in VHL-MUT-RCCs. A Representative tissue staining in VHL-WT (Ai-Aii) and VHL-MUT-RCC patients (Aiii-Aiv) (Magnification 200X detail 400x). B NKp46+ cell densities [NKp46+ cells/mm2] in RCC patients grouped in VHL-WT (n = 8) and VHL-MUT (n = 15). The results are presented as mean ± SEM; p = 0.0041, Mann–Whitney test. C-D mRNA expression of NKp30 and NKp46 in 17 VHL-WT and 17 VHL-MUT RCC patients. Transcript levels are presented as mean ± SEM. Statistical significance was calculated by unpaired Student t test (p < 0.05)

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