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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: EBV-miR-BART8-3p induces epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma cells through activating NF-κB and Erk1/2 pathways

Fig. 2

EBV-miR-BART8-3p promotes NPC cell migration and invasion in vitro and lung metastasis in vivo. a qPCR assay reveals higher EBV-miR-BART8-3pexpression in NPC specimens than in normal nasopharyngeal mucosal specimens (CTRL). b qPCR assay reveals higher EBV-miR-BART8-3p expression in NPC cells transfected withEBV-miR-BART8-3p precursors than in those transfected with control vectors. miRNA levels are normalized to U6 snRNA expression. c Representative images and quantification of the wound-healing assay in CNE-1 andSUNE-1cells. d Representative images and quantification of migration and invasion assays in CNE-1 andSUNE-1. e Representative images and quantification of the wound-healing assay in C666–1 cells. f Representative images and quantification of migration and invasion assays in C666–1 cells. ND, not detectable. Data is presented as the mean ± SD. ** P < 0.01; *** P < 0.001

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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