Fig. 4

Central cellular metabolism alteration in lung cancer cell lines endogenously harbouring these oncogenic alterations: H23 (KS), H1792 (K), H358 (K) H1563 (S) and H1993 (S). Significant metabolites differences were computed using Mann-Whitney-Wilcoxon Test). Measured metabolites are labelled as color-coded circle. Colours correspond to the fold-change in abundance relative to the single K or S: red, increase; blue, decrease; black, not measured; grey, measured but not statistically significant. Metabolites are reported using standard abbreviation