Fig. 5
From: miR-296-5p suppresses EMT of hepatocellular carcinoma via attenuating NRG1/ERBB2/ERBB3 signaling
miR-296-5p suppresses EMT and metastasis through NRG1. The miR-296-5p-KD Huh7 cells were transfected with siNRG1 and control siRNA, the miR-296-5p-OE MHCC97H cells were transfected with NRG1-expressing plasmids or the control plasmids for 48 h. The NRG1, secreted NRG1 proteins levels (a), EMT-associated morphological changes (b), EMT markers (E-cadherin and Vimentin) (c), the cellular metastasis (d) and motion ability (e) in the indicated cells. Magnification 200×. *p < 0.05, **p < 0.01, ***p < 0.001