Fig. 6From: Hypermethylation of DMTN promotes the metastasis of colorectal cancer cells by regulating the actin cytoskeleton through Rac1 signaling activationThe mechanisms of DMTN in the invasion and metastasis of CRC. Hypermethylation and the deletion of DMTN relieved its binding to the ARHGEF2 protein, activated the Rac1 signaling pathway, regulated actin cytoskeletal rearrangements, and finally promoted the invasion and metastasis of CRC cellsBack to article page