Fig. 1

Increased nuclear localization of YAP in human gastric carcinoma tissues compared with their adjacent normal tissues as determined by immunohistochemistry staining. a Representative images of YAP protein in adjacent noncancerous tissues, early stage and advanced stage of gastric tumor (Magnification 200×, Scale bars = 50 μm). b Quantitative analysis of YAP expression in paired cancer and noncancerous tissues. c, d YAP immunohistochemical scores at different invasion depth (C) or at different degrees of lymph node metastasis (d)