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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Hepatocellular carcinoma-derived exosomal miRNA-21 contributes to tumor progression by converting hepatocyte stellate cells to cancer-associated fibroblasts

Fig. 3

Tumor-derived exosomes activated HSCs in vitro. Wound-healing assays (a) and migration assay (b) of HSCs treated with equal quantities of exosomes derived from different liver cancer cells or blank control. c – h Xenograft assays of Huh7 with indicated treatments were performed on nude mice. Representative tumors, tumor volume and number of tumor nudes were shown. Experiments were performed at least in triplicate, and results are shown as mean ± s.d. Student’s t-test was used to analyze the data (NS, not significant; *p < 0.05; **p < 0.01; ***p < 0.001)

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