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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Promoter hypomethylation mediated upregulation of MicroRNA-10b-3p targets FOXO3 to promote the progression of esophageal squamous cell carcinoma (ESCC)

Fig. 3

miR-10b-3p overexpression promoted cell proliferation, colony formation and migration. a RNA level of miR-10b-3p in 7 ESCC cell lines. b Quantitation of the miR-10b-3p level after transfection of the miR-10b-3p mimic in KYSE150 and KYSE450 cell lines. c The cell growth curve was measured by MTS after transfection of the miR-10b-3p mimic in KYSE150 and KYSE450 cell lines, and the OD 570 was normalized to the star point (0 h). d Representative images and quantitation of colony formation were performed after transfection of the miR-10b-3p mimic in KYSE150 and KYSE450 cell lines. e Representative images and quantitation of the transwell assay were performed after transfection of the miR-10b-3p mimic in KYSE150 and KYSE450 cell lines. Each experiment was performed in triplicate. Data are presented as the mean value ± SD. , P < 0.05; , P < 0.01

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