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Table 3 The serum of miR-10b-3p expression status and clinicopathological characteristics of patients with ESCC

From: Promoter hypomethylation mediated upregulation of MicroRNA-10b-3p targets FOXO3 to promote the progression of esophageal squamous cell carcinoma (ESCC)

Characteristics

miR-10b-3p expression status

Low (n = 46)

High (n = 46)

P

Gender

 Male

33 (47.8%)

36 (52.2%)

0.470

 Female

13 (56.5%)

10 (43.5%)

Age

 <60

19 (44.2%)

24 (55.8%)

0.296

  ≥ 60

27 (55.1%)

22 (44.9%)

Tumor size

 < 5 cm

31 (51.7%)

29 (77.5%)

0.662

  ≥ 5 cm

15 (22.5%)

17 (22.5%)

Tumor stage

 T1+ T2

18 (60.0%)

12 (40.0%)

0.182

 T3+ T4

28 (45.2%)

34 (54.8%)

Histological grade

 Well/moderate

36 (53.7%)

31 (46.3%)

0.241

 Poor/NS

10 (40.0%)

15 (60.0%)

Lymph node metastasis

 Negative

26 (65.0%)

14 (35.0%)

0.012

 Positive

20 (38.5%)

32 (61.5%)

Clinical stages

 I + II

37 (69.8%)

16 (30.2%)

0.000

 III + IV

9 (23.1%)

30 (76.9%)