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Table 4 Correlation between FOXO3 expression and clinicopathological parameters of ESCC patients

From: Promoter hypomethylation mediated upregulation of MicroRNA-10b-3p targets FOXO3 to promote the progression of esophageal squamous cell carcinoma (ESCC)

Characteristics FOXO3 expression status
Low (n = 71) High (n = 32) P
Gender
 Male 60 (70.6%) 25 (29.4%) 0.430
 Female 11 (61.1%) 7 (38.9%)
Age
 <60 25 (71.4%) 10 (28.6%) 0.700
  ≥ 60 44 (67.7%) 21 (32.3%)
Tumor size
 < 5 cm 41 (69.5%) 18 (30.5%) 0.899
  ≥ 5 cm 28 (68.3%) 13 (31.6%)
Tumor stage
 T1+ T2 7 (58.3%) 5 (41.7%) 0.399
 T3+ T4 64 (70.3%) 27 (29.7%)
Histological grade
 Well/moderate 51 (68.0%) 24 (32.0%) 0.738
 Poor/NS 20 (68.9%) 8 (28.6%)
Lymph node metastasisa
 Negative 26 (56.5%) 20 (43.5%) 0.011
 Positive 44 (80.0%) 11 (20.0%)
Clinical stagesa
 I + II 22 (56.4%) 17 (43.6%) 0.026
 III + IV 48 (69.3%) 14 (30.7%)
  1. aNumbers do not equal to the total number due to missing data