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Table 2 Correlation between miR-194-5p expression and clinicopathologic chacteristics in 60 CCA patients

From: Tetraspanin 1 promotes epithelial-to-mesenchymal transition and metastasis of cholangiocarcinoma via PI3K/AKT signaling

Variabls

miR-194-5p expression

Low(n = 45)

High(n = 15)

P value

n(%)

n(%)

Age (years)

 > 60

28(62.22%)

10(66.67%)

0.7571

 ≤ 60

17(37.78%)

5(33.33%)

 

Gender

 Male

25(55.56%)

7(46.67%)

0.5501

 Female

20(44.44%)

8(53.33%)

 

Histological differentiation

 Well

12(26.67%)

6(40.00%)

0.2940

 Moderate

14(31.11%)

6(40.00%)

 

 Poor

19(42.22%)

3(20.00%)

 

TNM stage

 I-II

18(40.00%)

12(80.00%)

0.0073

 III-IV

27(60.00%)

3(20.00%)

 

CA19–9 (U/ml)

 ≤ 37

11(24.44%)

7(46.67%)

0.1038

 > 37

34(75.56%)

8(53.33%)

 

Lymph node metastasis

 No

20(44.44%)

13(86.67%)

0.0044

 Yes

25(55.56%)

2(13.33%)

 

Distant metastasis

 No

32(71.11%)

14(93.33%)

0.0780

 Yes

13(28.89%)

1(6.67%)

 
  1. Boldface indicates statistically significant values (P < 0.05)