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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Dysregulation of miR-6868-5p/FOXM1 circuit contributes to colorectal cancer angiogenesis

Fig. 3

Inhibition of miR-6868-5p promotes CRC angiogenesis. a and b HUVECs were treated with the CM from HCT8 or HCT116 cells transfected with indicated miRNA inhibitors. Cell viability (a) and migration ability (b) of HUVECs were measured by CCK8 assay and wound healing assay respectively. Scale bar = 20 μm. c HUVECs were co-cultured with HCT8 or HCT116 cells transfected with indicated miRNA inhibitors in transwell apparatus. Migrated HUVECs were quantified after co-culture for 24 h. Scale bar = 20 μm. d HUVECs were treated with the CM from indicated cells, and subjected to tube formation assay. Scale bar = 20 μm.*p < 0.05, **p < 0.01

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