Fig. 4

Analyses of DNMT1, DNMT3a, HDAC1 and HDAC2 on Saos2 and MG63 cell lines after VPA and DAC treatment. (a) Western blotting for DNMT1 and DNMT3a showing no change in the expression of DNMT1 and a decrease of DNMT3a expression; (b) Western blotting for HDAC1 and HDAC2 showing no change in the expression of HDAC1 and a decrease of HDAC2 expression. ** p < 0.001 compared to the untreated cells