Fig. 3
From: TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness
Aggressiveness driven de-regulation of transcriptome in melanoma cells behaving and functional analyses of the results. a Heat map of differentially expressed transcripts in A375 vsSK-MEL-28 human melanoma cells according to log2 AVG signals (left) and fold-change (right). b Graph showing most significantly enriched molecular functions identified by the IPA analysis. Each histogram reports the –log of the p-value (Fisher’s exact test) for each molecular function. The straight orange lines mark the significance p-value threshold (0.05)