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Table 3 IPA analysis of quantitative cytokines level expression

From: TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness

IPA ANALYSIS

p-value

Disease and Function

Cell-To-Cell Signaling and Interaction

8,54E-36

 

Inflammatory Response

4,1E-34

 

Cellular Growth and Proliferation

7,23E-34

 

Tumor Morphology

8,19E-24

 

Cell Signaling

1,18E-20

 

Molecular Transport

1,18E-20

 

Cellular Function and Maintenance

1,52E-18

 

Cell Morphology

1,48E-12

 

Cellular Assembly and Organization

1,05E-10

 

Protein Synthesis

7,14E-10

 
 

p-value

z-score

Pathways

Colorectal Cancer Metastasis Signaling

1,73E-02

2000

PPAR Signaling

4,44E-02

1000

LXR/RXR Activation

4,13E-02

0,447

Dendritic Cell Maturation

4,14E-02

0,378

  

Score

Network

Cell-To-Cell Signaling and Interaction

 

30

Cardiovascular System Development and Function/Tissue morphology

 

15