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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: RER1 enhances carcinogenesis and stemness of pancreatic cancer under hypoxic environment

Fig. 4

RER1 promotes PC malignance through regulation of EMT and CSC pathway. (a-c) RER1 overexpression or knockdown PANC-1 and MIA PaCa-2 cells were subjected to Western blot and qRT-PCR analyses of E-cadherin, N-cadherin, vimentin, snail, claudin-1 and actin. (d-f) RER1 overexpression or knockdown PANC-1 and MIA PaCa-2 cells were subjected to Western blot and qRT-PCR analyses of Sox2, Bmi1, Lin28, Nanog and actin. One representative of at least three independent experiments with similar results is shown. *P < 0.05; **P < 0.01 (Student’s t-test)

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