Skip to main content
Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Isoalantolactone induces apoptosis through ROS-mediated ER stress and inhibition of STAT3 in prostate cancer cells

Fig. 3

IATL activates ER stress pathway in prostate cancer cells. a-b PC-3 cells were treated with IATL for 4 h, the protein levels of p-eIF2α and ATF4 were determined by western blot. c-d DU145 cells were treated with IATL for 4 h, the protein levels of p-eIF2α and ATF4 were determined by western blot. e PC-3 cells were treated with IATL for 6 h. The mRNA expression of CHOP was analyzed by qRT-PCR. f PC-3 cells were treated with IATL for 12 h, the protein level of CHOP was determined by western blot. The results shown are representative of at least three independent experiments

Back to article page