Fig. 7

IATL inhibits DU145 xenograft tumor growth in vivo. a-b IATL treatment significantly inhibited tumor volume (a) and tumor weight (b) of DU145 human prostate cancer xenografts in nude mice, but did not affect body weight (c) of mice. d HE staining of the major organs, magnification 20x. e The levels of MDA in the tumor tissues. f Caspase-3 activity in the tumor tissues was determined by an assay kit using specific substrate. g The mRNA expression of CHOP in the tumor tissues. h-i Western blot analysis on the expression of CHOP from respective tumor tissue lysates. GAPDH was used as protein loading control. j-k Western blot analysis on the expression of p-STAT3 and STAT3 from respective tumor tissue lysates. GAPDH was used as protein loading control