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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Epigenetic reprogramming of epithelial mesenchymal transition in triple negative breast cancer cells with DNA methyltransferase and histone deacetylase inhibitors

Fig. 1

DNMTi and HDACi treatment inhibit proliferation, migration, and invasion of TNBC cells. a Schematic representation of the cell treatment for in vitro phenotypic studies. b Tables show the IC50 of the compounds and the concentrations used for in vitro assays. c Representative images of wound healing assay. Magnification, 40×. Scale bar, 60 μm. d-e Quantification of wound healing assay. f Representative images of Matrigel invasion assay and quantification of the invaded cells. Scale bar, 100 μm. (40×). *indicates p < 0.05, **indicates p < 0.01 compared to control. All experiments were repeated at least twice and one representative experiment is shown in the figure. This also applies to the experiments shown in other figures

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