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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: Downregulation of miRNA-214 in cancer-associated fibroblasts contributes to migration and invasion of gastric cancer cells through targeting FGF9 and inducing EMT

Fig. 2

MiR-214 suppressed the migration and invasion but not proliferation ability of GC cells. a Expression of miR-214 was significantly downregulated in CAFs than in paired NFs. b The ectopic expression of miR-214 in CAFs transfected with miR-214 mimics was confirmed by qRT-PCR. c, d and e The CCK8 and EdU assays showed that CAFsmiR-214-CM did not influence the proliferation of MGC-803 and SGC-7901 cells compared with CAFsNC-CM (no significant difference, NS, P > 0.05). f and g CAFsmiR-214-CM markedly inhibited the migration and invasion of MGC-803 and SGC-7901 cells compared with CAFsNC-CM (**P < 0.01)

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