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Table 1 Characteristics of 104 NSCLC patients in real-time quantitative RT-PCR analysisa

From: Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis

Parameter No. of patients Low Slug (%) High Slug (%) P Low Ubc9 (%) High Ubc9(%) P
Number of patients 104 66 (63.5) 38 (36.5)   48 (46.2) 56 (53.8)  
Sex
 Male 77 46 (69.7) 31 (81.6)   37 (77.1) 40 (71.4)  
 Female 27 20 (30.3) 7 (18.4) 0.183 11 (22.9) 16 (28.6) 0.512
Histological type
 Squamous cell carcinoma 37 19 (28.8) 18 (47.4)   19 (39.6) 18 (32.1)  
 Adenocarcinoma 62 44 (66.7) 18 (47.4)   28 (58.3) 34 (60.7)  
 Others 5 3 (4.6) 2 (5.3) 0.144 1 (2.1) 4 (7.1) 0.406
Tumor sizeb
 ≤ 3 cm 7 5 (7.7) 2 (5.3)   2 (4.3) 5 (8.9)  
 > 3 cm 96 60 (92.3) 36 (94.7) 0.637 45 (95.7) 51 (91.1) 0.348
Tumor stagec
 Stage I 42 32 (50.0) 10 (26.3)   22 (46.8) 20 (36.4)  
 Stage II 20 11 (17.2) 9 (23.7)   8 (17.0) 12 (21.8)  
 Stage III–IV 40 21 (32.8) 19 (50.0) 0.062 17 (36.2) 23 (41.8) 0.556
Slug expression
 Low 66     38 (79.2) 28 (50.0)  
 High 38     10 (20.8) 28 (50.0) 0.002
Ubc9 expression
 Low 48 38 (57.6) 10 (26.3)     
 High 56 28 (42.4) 28 (73.7) 0.002    
  1. aP values were calculated using a two-sided Pearson Chi-Squared test. Slug and Ubc9 expression was designated as ‘high’ or ‘low’ using 0.6 as the cut-off point
  2. bOne patient’ tumor size state was missing
  3. cTwo patients’ tumor stage states were missing